Orfadin

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Orfadin

Facts of Orfadin ?

  • Medicine Name: Orfadin
  • Generic Name: Nitisinone
  • Company Name: Sweden Orphan International AB
  • Available as (Form & Strength): 2mg/5mg/10mg, 60 Caps/61 Caps/62 Caps
Category:

Product Description

WHAT ARE THE INDICATIONS?

Heriditary tyrosinemia type (HT-1) – adjunct to dietary reduction of tyrosine and phenylamine in
the treatment of HT-1

WHAT ARE THE DOSAGES?

  • Dose should be adjusted in each patient.
  • The recommended initial dosage is 1mg/kg/day divided for morning and evening administration.
    Since the effect of food is unknown , nitisone should be taken at least 1 hour before a meal.

PATIENT INFORMATION:

1. Advice patients and their caregivers of the need to maintain dietary resriction of tyrosine and
phenylalanine when taking nitisinone to treat HT-1
2. Advice patients and their caregivers to promptly report unexplained eye symptoms , rash,
jaundice, oe excessive bleeding

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