• Zelboraf


Facts of Zelboraf (Vemurafenib) Tablets 240 mg ?

  • Medicine Name: ZELBORAF
  • Generic Name: VEMURAFENIB
  • Date of Approval: 17.08.2011
  • Company Name: ROCHE.

Product Description

What is Zelboraf ?

ZELBORAF (vemurafenib) is a kinase inhibitor available as 240 mg tablets for oral use. Vemurafenib has the chemical name propane-1-sulfonic acid {3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4­ difluoro-phenyl}-amide. It has the molecular formula C23H18ClF2N3O3S and a molecular weight of 489.9

What are the indications and usage?

ZELBORAF™ is a kinase inhibitor indicated for the treatment of patients with unresectable or metastatic melanoma with BRAFV600E mutation as detected by an FDA-approved test

Limitation of Use: ZELBORAF is not recommended for use in patients with wild-type BRAF melanoma

How supplied/storage and handling ?

ZELBORAF (vemurafenib) is supplied as 240 mg film-coated tablets with VEM debossed on one side in single bottle of 120 count. The following packaging configuration is available:

Storage and Stability: Store at room temperature 20°C – 25°C (68°F – 77°F); excursions permitted between 15°C and 30°C (59°F and 86°F), See USP Controlled Room Temperature. Store in the original container with the lid tightly closed.
Disposal of unused/expired medicines: The release of pharmaceuticals in the environment should be minimized. Medicines should not be disposed of via waste-water and disposal through household waste should be avoided. Use established “collection systems”, if available in your location.


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