Facts of ADCETRIS Brentuximab Vedotin ?

  • Medicine Name: Adcetris
  • Date of Approval:19.08.2011
  • Company Name: Seattle Genetics, Inc.
  • Treatment of: Hodgkin Lymphoma; Systemic Anaplastic Large Cell Lymphoma.

Product Description

What is ADCETRIS Brentuximab Vedotin ?

Adcetris contains the active substance brentuximab vedotin, an anti-cancer agent, which is made up of a monoclonal antibody linked to a substance intended to kill cancer cells. This substance is delivered to cancer cells by the monoclonal antibody. A monoclonal antibody is a protein which recognises certain cancer cells.

What are the indications and usage?

Adcetris is used to treat classical Hodgkin lymphoma that has:

  • come back after or not responded to an infusion of your own healthy stem cells into your body (autologous stem cell transplant), or
  • come back after or never responded to at least two previous therapies, and where you cannot receive additional combination anti-cancer treatments or have an autologous stem cell transplant.

Classical Hodgkin lymphoma expresses specific proteins on the cell surface that are different from non-classical Hodgkin lymphoma.

Adcetris is used to treat systemic anaplastic large cell lymphoma which is found in your lymph nodes and/or throughout other parts of your body that has:

  • not responded to other types of anti-cancer treatments, or
  • come back after previous anti-cancer treatment.

Hodgkin lymphoma and systemic anaplastic large cell lymphoma are both types of cancer of the white blood cells.

How supplied/storage and handling ?

Adcetris is a white to off-white cake or powder for concentrate for solution for infusion provided in a glass vial. Each pack of Adcetris consists of one vial.

Store in a refrigerator (2°C-8°C). Do not freeze. Keep the vial in the original carton in order to protect from light.For storage conditions after reconstitution and dilution of the medicinal product, see section 6.3.


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